Meet the Niko Hildebrandt lab team

Research interests: Solid state physics, computational physics, materials characterization and nanofabrication, thin film deposition, optics and electro-optical devices

Research interests: DNA scaffolds, polymer chemistry, analytical chemistry, biomedical devices, nano fabrication and characterisation, bacteria detection, DNA amplification techniques

Research interests: Dendrimers for biological applications, FRET, organic chemistry & synthesis

Research interests: FRET and nanoparticles characterization

Research interests: Material science, Steady-state and time resolved spectroscopy, laser gain media characterization, hyperspectral imaging, FRET systems

Research interests: Improving medical diagnostics, specifically in the area of wearable technology. The accurate and real-time measurement of potassium from interstitial fluid is my primary focus. Potassium is a crucial electrolyte that is needed for nerve conduction, muscle function and fluid homeostasis. Its measurement and management is key to good health and vitality. Serious adverse events can occur if this important mineral is not maintained within its narrow range. User-friendly, wearable technology will allow real-time results and instant intervention and prevent untoward outcomes.

Research interests: The properties of light and its interaction with matter. I am eager to unravel the mysteries of this fascinating field and contribute to the evolution of our understanding of light and its practical applications, especially in medical fields and for treatments.

Research interests: DNA structures, DNA backbone modifications, and nanoparticles. My research aim has been combining the experties of DNA with fluorescent materials and metal nanoparticles.

Research interests: Developing a competitive TR-FRET (Time Resolved-Förster Resonance Energy Transfer) assay for quality control in stem cell manufacturing and high-throughput screening with the Bio-techne group, applying a multiplexed RCA-TR-FRET (Rolling Circle Amplification TR-FRET) method for miRNA-based endometriosis diagnosis in collaboration with the Leonardi Research Group (FHS – Faculty of Health Sciences), designing a quadruplexed TR-FRET assay to measure antibodies concentrations in mice plasma by specificity, isotype, and expressed tag in collaboration with the Joshua Koenig Lab (FHS).

Research interests: Developing a FRET-based biosensor for the Early Detection of Renal Dysfunction, with strong interest for Kidnety health and renal function Assessment using emerging technologies. Also working on Optimizing the Interpretation of Troponin(cTnT) in patient with renal Impairment. and finally Optical Device for the detection of protein and DNA using Microfluidic Chip.

Research interests: My research specializations are in advanced light microscopy techniques, principally fluorescence microscopy techniques, biomolecular structure and interactions (DNA and protein), and rheometry/rheology.

Research interests: Developing rapid FRET biosensors for the point-of-care detection of bacterial infections and with broader applications in environmental monitoring.

Research interests: Water-Stable Halide Perovskite Nanocrystals in Polymer Nanoparticles

Research interests: Fundamental research about NIR FRET; FRET sensing and imaging applications

Research interests: Development of bright luminescent nanoprobes and their use in optical microscopy, for applications in bioimaging and biosensing

Research interests: Application of nanoparticles in analytical spectroscopy; Nanoparticle bioapplications, time-resolved and steady-state photoluminescence spectroscopy, Biological, environmental, chemical, and pharmaceutical analysis, development of novel biosensors for cancer early detection

Research interests: My current research focuses on the synthesis of metal halide perovskite nanoparticles and the investigation of their photophysical properties, with particular emphasis on understanding energy transfer mechanisms to surrounding media. A key aspect of this work involves enhancing their stability in polar solvents, which is essential for practical applications.

Research interests: My research is focused on the influence of nanoparticles on biological systems.
The first research project I am involved in is about the influence of gold nanoparticles (AuNPs) on fluorophore emission and potential quenching through the AuNPs scattering and absorption properties.
The second project is about the effect of AuNPs and quantum dots on aptamer-based DNAzymes and their impact on cleavage efficiency.

Research interests: TR-FRET techniques, biosensing and assay development

Research interests: Parasite and mosquito genetics, development of low cost genotyping methods for infectious disease applications ,with a focus on drug and insecticide resistance monitoring.

Research interests: Functional Dynamics of Molecules and Materials: Femtosecond and Picosecond time-resolved Laser spectroscopy, Biomolecules, Bio-Nano Interface and Self-organized molecular assembly, Light Harvesting, Dye Sensitized solar cells, and Instrumentation.

Research Interests: Modeling of Plasmon-Enhanced FRET on Gold Nanoparticles and Portable Time-Gated Fluorescence System

Research interests: focused on developing core-shell nanoparticle systems for enhanced optical properties. One of my projects focuses on the synthesis of polymer shells on gold nanoparticles to precisely tune the distance between the nanoparticle surface and the fluorophore to achieve fluorescence enhancement. My other project uses a similar approach to synthesize polymeric shells over polymer nanoparticles to improve their fluorescence intensity and stability in biologically-relevant media.

Research interests: Energy transfer engineering between organic dyes and lanthanide complexes. Polymeric nanoparticle encapsulation via nanoprecipitation. Photophysical optimization for improved upconversion efficiency and stability. Applications in biological imaging and molecular sensing

Research interests: My current research focuses on an NSET (Nanomaterial Surface Energy Transfer) system that uses a gold nanoparticle (AuNP) and DNA as a carrier for Terbium loading. The goal is to optimize this system for more accurate distance measurement as an effective nanoruler.

Research interests: Single fluorescent nanoparticle detection using fluorescence microscopy.

Research interests: The intersection of biosensing, fluorescence spectroscopy, nanomaterials and women’s health diagnostics. I am particularly interested in developing affordable, rapid and sensitive diagnostic tools for applications in food safety and hormonal health.

Research interests: Physiology and Physiological, Host-Pathogens Interactions- Tracking Bacterial Dynamics in Live Mice via FDAA Labelling and Immunohistological Imaging