My work focuses on assessment of normal and diseased tissue microstructure and the resultant modulation of tissue metabolism using medical imaging technologies. A great deal of my research involves MRI and in vivo nuclear magnetic resonance (NMR) spectroscopy. However, more recently I have focused on applications of multimodal techniques, or the fusion of MRI with EEG, EMG, ultrasound and other imaging methods. Overall I am interested in developing more comprehensive and diagnostically useful disease imaging protocols for evaluation of anatomic, metabolic and functional characteristics of healthy and abnormal tissues.
Did you know?
Dr. Noseworthy was the Co-Director of the McMaster School of Biomedical Engineering from 2010 to 2020.
He is also Special Professional Staff in Radiology and Nuclear Medicine, and Director of Medical Imaging Physics and Engineering at St. Joseph’s Healthcare
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Dr. Noseworthy received a M.Sc. from the University of Guelph for work in the evaluation of anaesthetic hepatotoxicity using nuclear magnetic resonance imaging (MRI) and in vivo 31P-NMR. Obtained a PhD from University of Guelph (1997) specializing in applications of MRI/NMR, biochemical assays and electron paramagnetic resonance (EPR) methods to assess free radical induced brain damage. From 1997-1999 was a postdoctoral fellow in Imaging Physics, Sunnybrook Health Sciences Centre working on the evaluation of tissue microvasculature through development of correlative MRI and energy dispersive X-ray microanalysis (EDXS). From January 2000 to August 2003 worked as a MRI physicist at The Hospital for Sick Children, Toronto, and Assistant Professor in Medical Biophysics and Medical Imaging, University of Toronto. Moved to St. Joseph’s Healthcare and Brain-Body Institute, McMaster University in August 2003. Following 3 years as an Assistant Professor in Radiology and Medical Physics at McMaster University, Dr. Noseworthy attained a tenure-track position in Electrical & Computer Engineering at McMaster University, where he currently resides as a full professor. His research interests include the assessment of tissue microstructure and metabolism using magnetic resonance imaging (MRI) and multinuclear in vivo nuclear magnetic resonance (NMR) spectroscopic techniques, and the application of complex systems mathematics and machine learning to medical image analysis. Dr. Noseworthy is a member of the Professional Engineers of Ontario (PEO), Institute of Electrical and Electronics Engineers (IEEE), International Society for Magnetic Resonance in Medicine (ISMRM) and European Society for Magnetic Resonance in Medicine and Biology (ESMRMB).
P.Eng. (L.E.L)
President’s Award for Excellence in Graduate Supervision (McMaster University, 2013)
Physical principles of medical image acquisition and formation; post-processing for magnetic resonance imaging and spectroscopy; comparisons to other medical imaging modalities. Three lectures, one tutorial, one lab every other week; second term Prerequisite(s): ELECENG 2FH3 or 2FH4, ELECENG 3TP4 or 3TP3; and registration in Level IV Electrical and Biomedical Engineering or Level IV and above in the Integrated Biomedical Engineering and Health Sciences (IBEHS) program or permission of the department. Antirequisite(s): ELECENG 4BF3
Physical principles of medical image acquisition and formation; post-processing for magnetic resonance imaging and spectroscopy; comparisons to other medical imaging modalities. Three lectures, one tutorial, one lab every other week; second term Prerequisite(s): ELECENG 2FH3 or 2FH4, ELECENG 3TP4 or 3TP3; and registration in Level IV Electrical and Biomedical Engineering or Level IV and above in the Integrated Biomedical Engineering and Health Sciences (IBEHS) program or permission of the department. Antirequisite(s): ELECENG 4BF3
Physical principles of medical image acquisition and formation; post-processing for magnetic resonance imaging and spectroscopy; comparisons to other medical imaging modalities. Three lectures, one tutorial, one lab every other week; second term Prerequisite(s): ELECENG 2FH3 or 2FH4, ELECENG 3TP4 or 3TP3; and registration in Level IV Electrical and Biomedical Engineering or Level IV and above in the Integrated Biomedical Engineering and Health Sciences (IBEHS) program or permission of the department. Antirequisite(s): ELECENG 4BF3
3 unit(s) M. Noseworthy (cross-listed as MED SCI 765) Functional brain imaging using magnetic resonance techniques (MIR, and in vivo NMR) will be thoroughly discussed. Advantages and disadvantages, relative to other brain imaging modalities (CT, PET, SPECT, NIRS, US) will be discussed where appropriate. This course will provide students with an appropriate, yet complete, understanding of the underlying physics surrounding magnetic resonance and its relevance to neuroscience for the design of functional brain imaging experiments.
Instructor
Dr. Michael Noseworthy
3 unit(s) Each week in this course an invited radiologist will speak on the current state of the art in a particular area of diagnostic medical imaging (e.g., musculoskeletal radiology, neuroradiology, interventional radiology, etc.). They will outline the approaches they use to diagnose and grade disease and the limitations of the technology, as they see it from a clinical perspective. This presentation will be followed (on a different day) by a synopsis and open discussion on how the technology is used, the limitations, and potential avenues or approaches on how students would improve the technology for better assessing disease.
Instructor
Dr. Michael Noseworthy
3 unit(s) (cross-listed as ECE 780 and MED PHYS 702 and BIOMED 702) This course will compliment Medical Imaging Systems I. In this course imaging methods that rely on non-ionizing radiation will be discussed. The course content focuses on magnetic resonance imaging (MRI), in vivo nuclear magnetic resonance (NMR), ultrasound (US), and optical imaging methods. Advanced concepts such as multi-modality imaging approaches, image fusion, and functional medical image processing will be discussed.
Instructor
Dr. Michael Noseworthy
3 unit(s) (cross-listed as ECE 780 and MED PHYS 702 and BIOMED 702) This course will compliment Medical Imaging Systems I. In this course imaging methods that rely on non-ionizing radiation will be discussed. The course content focuses on magnetic resonance imaging (MRI), in vivo nuclear magnetic resonance (NMR), ultrasound (US), and optical imaging methods. Advanced concepts such as multi-modality imaging approaches, image fusion, and functional medical image processing will be discussed.
Instructor
Dr. Michael Noseworthy
3 unit(s) Staff (cross-listed as ECE 6BC3) Introduction to mathematical and engineering methods for describing and predicting the behaviour of biological systems; including sensory receptors, neuromuscular and biomechanical systems; statistical models of biological function; kinetic models of biological thermo-dynamics.
Instructor
Dr. Michael Noseworthy
3 unit(s) Staff (cross-listed as ECE 6BC3) Introduction to mathematical and engineering methods for describing and predicting the behaviour of biological systems; including sensory receptors, neuromuscular and biomechanical systems; statistical models of biological function; kinetic models of biological thermo-dynamics.
