Dr. Kanwarpal Singh – Faculty of Engineering
Kanwarpal Singh headshot

Dr. Kanwarpal Singh


Optical coherence tomography, hyperspectral imaging, confocal microscopy, endoscopy, multiphoton microscopy

Research Clusters

  • Associate Professor

    Electrical & Computer Engineering


The focus of Dr. Singh’s lab is to develop novel endoscopic devices to image internal organs of the body. These endoscopes are based on optical imaging techniques such as optical coherence tomography, hyperspectral imaging, multiphoton imaging, etc.

Block Heading

Dr. Singh is currently working as Assistant Professor with the Department of Electrical and Computer Engineering, McMaster University. Before joining McMaster University, Dr. Singh lead an independent research group (Microendoscopy) at the Max Planck Institute for the Science of Light, Germany. His research group focused on the development of miniaturized flexible endoscopic devices for in vivo imaging. He finished his Ph.D. from INRS, Canada in 2013. He was a postdoctoral fellow at Harvard Medical School, USA until 2018 where he worked on the development of high-resolution optical coherence tomography systems. He was the recipient of the Doctoral research award from FRSQ and FQRNT. He also received Postdoctoral fellowships from FRSQ and CIHR. He has won several prestigious awards such as Innovation challenge award from Natural Sciences and Engineering Research Council (NSERC) of Canada.

  • BSc (Kurukshetra University, India)
  • MTech (Devi Ahilya University, India)
  • PhD (University of Quebec, Canada)

1. Innovation challenge award, Natural Sciences and Engineering Research Council (NSERC) of Canada, 2012

2. Innovation Award, Institut national de la recherche scientifique, Quebec, Canada. 2012

3. STELLA travel grant Italy, 2011

4. Incubic/Milton Chang travel grant, Optical Society of America, 2009

5. Ministère de l’Éducation, du Loisir et du Sport (MELS) travel grant 2009


1. A. Parmar, G. Sharma, A. Ramming and K. Singh, “Deep Tissue Characterization With Optical Coherence Elastography: A comparison of different methods,” Materials, 15(23), pp. 8558 (2022) https://doi.org/10.3390/ma15238558

2. M. N. Romodina, K. Blessing, and K. Singh, “Polarization maintaining fiber-based depth encoded cross-polarized optical coherence tomography,” IEEE Access, vol 10, pp. 132685. (2022) DOI: 10.1109/ACCESS.2022.3229974

3. M. N. Romodina and K. Singh, “Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide,” Journal of Biophotonics, e202200051, vol. 15, May 2022, https://doi.org/10.1002/jbio.202200051

4. G. Sharma, A. Parmar, F. Hoffmann, K.Geißler, F.Eggeling, O.Guntinas-Lichius, and K. Singh. “A Proposal to Perform High Contrast Imaging of Human Palatine Tonsil with Cross Polarized Optical Coherence Tomography,” Photonics, vol. 9(4), pp. 259, April 2022, https://doi.org/10.3390/photonics9040259

5. A.Parmar, G. Sharma and K. Singh, “Polarization Independent Optical Coherence Tomography,” IEEE Photonics Journal, vol. 14(2), pp. 3916805, April 2022, DOI: 10.1109/JPHOT.2022.3148721

6. G. R. Hartl, A. Parmar, G. Sharma, and K. Singh, “Cross-Polarized Optical Coherence Tomography System with Unpolarized Light,” Photonics, vol. 9(2), pp. 76, Jan. 2022, https://doi.org/10.3390/photonics9020076

7. K. Blessing, J. Schirmer, A. Parmar, and K. Singh, “Depth encoded input polarisation independent swept source cross-polarised optical coherence tomography probe,” Journal of Physics D: Applied Physics, vol. 54(30), pp. 305401, May 2021, https://doi.org/10.1088/1361-6463/abfc87

8. A. Parmar, G. Sharma, S. Sharma and K. Singh, “Portable Optical Coherence Elastography System With Flexible and Phase Stable Common Path Optical Fiber Probe,” IEEE Access, vol. 9, pp. 56041, Apr. 2021, DOI: 10.1109/ACCESS.2021.3071793

9. G. Sharma, S. K. Naveed, A. Parmar and K. Singh, “Chromatic Dispersion Based Wide-Band, Fiber-Coupled, Tunable Light Source for Hyperspectral Imaging,” IEEE Access, vol. 9, pp. 50538, Mar. 2021, DOI: 10.1109/ACCESS.2021.3068617

10. J. Dong, C. Grant, B. Vuong, N. Nishioka, A. H. Gao, M. Beatty, G. Baldwin, A. Baillargeon, A. Bablouzian, P. Grahmann, N. Bhat, E. Ryan, A. Barrios, S. Giddings, T. Ford, E. Beaulieu-Ouellet, S. H. Hosseiny, I. Lerman, W. Trasischker, R. Reddy, K. Singh, M. Gora, D. Hyun, L. Quénéhervé, M. Wallace, H. Wolfsen, P. Sharma, K. K. Wang, C. L. Leggett, J. Poneros, J. A. Abrams, C. Lightdale, S. Leeds, M. Rosenberg, and G. J. Tearney, “Feasibility and Safety of Tethered Capsule Endomicroscopy in Patients With Barrett’s Esophagus in a Multi-Center Study,” Clinical Gastroenterology and Hepatology, vol. 20(4), pp. 756, Apr. 2022, https://doi.org/10.1016/j.cgh.2021.02.008

11. G. Sharma, O.-M. Thoma, K. Blessing, R. Gal, M. Waldner, and K. Singh, “Smartphone-based multimodal tethered capsule endoscopic platform for white-light, narrow-band, and fluorescence/autofluorescence imaging,” Journal of Biophotonics, vol. 14(2), pp. online, Nov. 2020, https://doi.org/10.1002/jbio.202000324

12. K. Blessing, J. Schirmer, G. Sharma, and K. Singh, “Novel input polarisation independent endoscopic cross polarised optical coherence tomography probe,” Journal of Biophotonics, vol. 13(12), pp. online, Dec. 2020, https://doi.org/10.1002/jbio.202000134

13. M. M. Chowdhury, K. Singh, M. S. Albaghdadi, H. Khraishah, A. Mauskapf, C. W. Kessinger, E. A. Osborn, S. Kellnberger, Z. Piao, C. L. Lino Cardenas, M. S. Grau, M. R. Jaff, K. Rosenfield, P. Libby, E. R. Edelman, M. E. Lindsay, G. J. Tearney, and F. A. Jaffer, “Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits,” JACC: Basic to Translational Science, vol. 5(7), pp. 696, Jul. 2020, https://doi.org/10.1016/j.jacbts.2020.04.007

14. S. Sharma, G. Hartl, S. K. Naveed, K. Blessing, G. Sharma, and K. Singh, “Input polarization-independent polarization-sensitive optical coherence tomography using a depolarizer,” Review of Scientific Instruments, vol. 91, pp. 043706, Mar. 2020, https://doi.org/10.1063/5.0001871

15. G. Sharma, S. Sharma, K. Blessing, G. Hartl, M. Waldner, and K. Singh, “Swept source cross-polarized optical coherence tomography for any input polarized light,” Journal of Optics, vol. 22(4), pp. 045301, Mar. 2020, https://doi.org/10.1088/2040-8986/ab746a

16. K. Blessing, S. Sharma, A. Gumann, and K. Singh, “Low cost scalable monolithic common path probe design for the application in endoscopic optical coherence tomography,” Engineering Research Express, vol. 1(2), pp. 025008, Oct. 2019, https://doi.org/10.1088/2631-8695/ab4783

17. D. O. Otuya, G. Sharma, G. J. Tearney, and K. Singh, “All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch,” OSA Continuum , vol. 2(12), pp. 3465, Dec. 2019, https://doi.org/10.1364/OSAC.2.003465

18. C. P. Liang, J. Dong, T. Ford, R. Reddy, H. Hosseiny, H. Farrokhi, M. Beatty, K. Singh, H. Osman, B. Vuong, G. Baldwin, C. Grant, S. Giddings, M. J. Gora, M. Rosenberg, N. Nishioka, and G. Tearney, “Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients,” Biomedical Optics Express, vol. 10, pp. 1207, Feb. 2019, https://doi.org/10.1364/BOE.10.001207

19. J. A. Gardecki, K. Singh, C.-L. Wu, and G. J. Tearney, “Imaging the Human Prostate Gland Using 1-μm-Resolution Optical Coherence Tomography,” Archives of pathology & laboratory medicine, vol. 143(3), pp. 314, Mar. 2019, https://doi.org/10.5858/arpa.2018-0135-OA

20. K. Singh, G. Sharma, and G. J. Tearney, “Estimation and compensation of dispersion for a high-resolution optical coherence tomography system,” Journal of Optics, vol. 20, pp. 025301, Jan. 2018, https://doi.org/10.1088/2040-8986/aaa2c0

21. K. Singh, R. Reddy, G. Sharma, Y. Verma, J. A. Gardecki, and G. Tearney, “In‐line optical fiber metallic mirror reflector for monolithic common path optical coherence tomography probes,” Lasers in surgery and medicine, vol. 50, pp. 230, Mar. 2018, https://doi.org/10.1002/lsm.22756

22. K. Singh, D. Yamada, and G. Tearney, “Astigmatism corrected common path probe for optical coherence tomography,” Lasers in surgery and medicine, vol. 49, pp. 312, Aug 2016, https://doi.org/10.1002/lsm.22554

23. B. Yin, K. K. Chu, C.-P. Liang, K. Singh, R. Reddy, and G. J. Tearney, “μOCT imaging using depth of focus extension by self-imaging wavefront division in a common-path fiber optic probe,” Optics express, vol. 24, pp. 5555, Mar. 2016, https://doi.org/10.1364/OE.24.005555

24. A. Ibrahim, G. Sharma, K. Singh, and T. Ozaki, “Terahertz detection based on spectral-domain interferometry using Mach-Zehnder interferometer,” Journal of Infrared, Millimeter, and Terahertz Waves, vol. 37, pp. 837, Apr. 2016, https://doi.org/10.1007/s10762-016-0275-8

25. K. K. Chu, C. Unglert, T. N. Ford, D. Cui, R. W. Carruth, K. Singh, L. Liu, S. E. Birket, G. M. Solomon, and S. M. Rowe, “In vivo imaging of airway cilia and mucus clearance with micro-optical coherence tomography,” Biomedical optics express, vol. 7, pp. 2494, Jun. 2016, https://doi.org/10.1364/BOE.7.002494

26. A. Ibrahim, G. Sharma, K. Singh, M. Kirouac-Turmel and T. Ozaki, “Ultra-high dynamic range electro-optic sampling for detecting millimeter and sub-millimeter radiation,” Scientific Reports, vol. 6, pp. 23107 Mar. 2016, https://doi.org/10.1038/srep23107

27. K. Singh, D. Yamada, and G. Tearney, “Common Path Side Viewing Monolithic Ball Lens Probe for Optical coherence tomography,” Medical Technologies in Medicine, vol. 7, pp. 29, 2015, https://doi.org/10.17691/stm2015.7.1.0

28. L. Jay, J.-M. Bourget, B. Goyer, K. Singh, I. Brunette, T. Ozaki, and S. Proulx, “Characterization of tissue-engineered posterior corneas using second-and third-harmonic generation microscopy,” PloS one, vol. 10(4), pp. online, Apr. 2015, https://doi.org/10.1371/journal.pone.0125564

29. K. Singh, N. Haydari, I. Brunette, and S. Costantino, “Preparing uniform-thickness corneal endothelial grafts from donor tissues using a non-amplified femtosecond laser,” PloS one, vol. 8, vol. 8(12), pp. online, Dec. 2013, https://doi.org/10.1371/journal.pone.0083185

30. G. Sharma, K. Singh, A. Ibrahim, I. Al-Naib, R. Morandotti, F. Vidal, and T. Ozaki, “Self-referenced spectral domain interferometry for improved signal-to-noise measurement of terahertz radiation,” Optics letters, vol. 38, pp. 2705, Jul. 2013, https://doi.org/10.1364/OL.38.002705

31. C. Dion, K. Singh, T. Ozaki, M. R. Lesk, and S. Costantino, “Analysis of pulsatile retinal movements by spectral-domain low-coherence interferometry: influence of age and glaucoma on the pulse wave,” PloS one, vol. 8, pp. online, Jan. 2013, https://doi.org/10.1371/journal.pone.0054207

32. K. Singh, C. Dion, A. G. Godin, F. Lorghaba, D. Descovich, M. Wajszilber, T. Ozaki, S. Costantino, and M. R. Lesk, “Pulsatile movement of the optic nerve head and the peripapillary retina in normal subjects and in glaucoma,” Investigative ophthalmology & visual science, vol. 53, pp. 7819, Nov. 2012, https://doi.org/10.1167/iovs.12-9834

33. G. Sharma, K. Singh, I. Al-Naib, R. Morandotti, and T. Ozaki, “Terahertz detection using spectral domain interferometry,” Optics letters, vol. 37, pp. 4338, Oct. 2012, https://doi.org/10.1364/OL.37.004338

34. K. Singh, C. Dion, M. Wajszilber, T. Ozaki, M. R. Lesk, and S. Costantino, “Measurement of ocular fundus pulsation in healthy subjects using a novel Fourier-domain optical coherence tomography,” Investigative ophthalmology & visual science, vol. 52, pp. 8927, Nov. 2011, https://doi.org/10.1167/iovs.11-7854

35. K. Singh, C. Dion, M. Lesk, T. Ozaki, and S. Costantino, “Spectral-domain phase microscopy with improved sensitivity using two-dimensional detector arrays,” Review of Scientific Instruments, vol. 82, pp. 023706, Feb. 2011, https://doi.org/10.1063/1.3556787

36. J. Mazzaferri, D. Kunik, J. Belisle, K. Singh, S. Lefrançois, and S. Costantino, “Analyzing speckle contrast for HiLo microscopy optimization,” Optics express, vol. 19, pp. 14508, Jul. 2011, https://doi.org/10.1364/OE.19.014508

37. F. Ferri, A. D’Angelo, M. Lee, A. Lotti, M. Pigazzini, K. Singh, and R. Cerbino, “Kinetics of colloidal fractal aggregation by differential dynamic microscopy,” The European Physical Journal-Special Topics, vol. 199, pp. 139, Dec, 2011, https://doi.org/10.1140/epjst/e2011-01509-9

38. K. Singh, C. Dion, S. Costantino, M. Wajszilber, M. Lesk, and T. Ozaki, “Development of a novel instrument to measure the pulsatile movement of ocular tissues,” Experimental eye research, vol. 91, pp. 63-68, Jul. 2010, https://doi.org/10.1016/j.exer.2010.03.022

39. L. Jay, A. Brocas, K. Singh, J.-C. Kieffer, I. Brunette, and T. Ozaki, “Determination of porcine corneal layers with high spatial resolution by simultaneous second and third harmonic generation microscopy,” Optics express, vol. 16, pp. 16284, Sep. 2008, https://doi.org/10.1364/OE.16.016284

40. L. M. Rivas, K. Singh, A. Carballar, and J. Azaña, “Arbitrary-order ultrabroadband all-optical differentiators based on fiber Bragg gratings,” IEEE Photonics Technology Letters, vol. 19, pp. 1209, Jul. 2007, DOI: 10.1109/LPT.2007.901746